- Conditions
- Dim Light Vision Disturbances
- Interventions
- Phentolamine Ophthalmic Solution 0.75%, Phentolamine Ophthalmic Solution Vehicle (Placebo)
- Drug
- Lead sponsor
- Ocuphire Pharma, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 144 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 17
- States / cities
- Newport Beach, California • Petaluma, California • Jacksonville, Florida + 12 more
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.
These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Showing 1–9
of 9
matching trials from the live ClinicalTrials.gov search.
- Conditions
- Mydriasis, Dilation
- Interventions
- Phentolamine Ophthalmic Solution 0.75%, Phentolamine Ophthalmic Solution Vehicle
- Drug
- Lead sponsor
- Ocuphire Pharma, Inc.
- Industry
- Eligibility
- 12 Years and older
- Enrollment
- 368 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2022
- U.S. locations
- 15
- States / cities
- Newport Beach, California • Westminster, California • Delray Beach, Florida + 12 more
- Conditions
- Mydriasis, Dilation
- Interventions
- Phentolamine Ophthalmic Solution 0.75%, Phentolamine Ophthalmic Solution Vehicle (Placebo)
- Drug · Other
- Lead sponsor
- Ocuphire Pharma, Inc.
- Industry
- Eligibility
- 12 Years and older
- Enrollment
- 185 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2021
- U.S. locations
- 12
- States / cities
- Newport Beach, California • San Diego, California • Longwood, Florida + 9 more
- Conditions
- Mydriasis, Dilation
- Interventions
- Phentolamine Ophthalmic Solution 0.75%, Phentolamine Ophthalmic Solution Vehicle
- Drug
- Lead sponsor
- Ocuphire Pharma, Inc.
- Industry
- Eligibility
- 3 Years to 11 Years
- Enrollment
- 23 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2022
- U.S. locations
- 2
- States / cities
- Longwood, Florida • Athens, Ohio
- Conditions
- Mesopic Vision, Night Vision Loss
- Interventions
- phentolamine ophthalmic solution 0.75%, a non-selective alpha-1 and alpha-2 adrenergic antagonist, Placebo
- Drug
- Lead sponsor
- Ocuphire Pharma, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 25
- States / cities
- Pheonix, Arizona • Scottsdale, Arizona • Bakersfield, California + 20 more
- Conditions
- Vision Loss Night, Vision Disorders
- Interventions
- 0.75% Phentolamine Ophthalmic Solution, Placebo
- Drug
- Lead sponsor
- Ocuphire Pharma, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 580 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 20
- States / cities
- Chandler, Arizona • Phoenix, Arizona • Scottsdale, Arizona + 16 more
- Conditions
- Presbyopia
- Interventions
- Phentolamine Ophthalmic Solution 0.75%, Pilocarpine, Placebo
- Drug · Other
- Lead sponsor
- Ocuphire Pharma, Inc.
- Industry
- Eligibility
- 40 Years to 64 Years
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021
- U.S. locations
- 17
- States / cities
- Laguna Hills, California • Newport Beach, California • Crystal River, Florida + 14 more
- Conditions
- Presbyopia
- Interventions
- 0.75% phentolamine ophthalmic solution, Placebo
- Drug
- Lead sponsor
- Ocuphire Pharma, Inc.
- Industry
- Eligibility
- 45 Years to 64 Years
- Enrollment
- 569 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2026
- U.S. locations
- 39
- States / cities
- Chandler, Arizona • Mesa, Arizona • Phoenix, Arizona + 32 more
- Conditions
- Presbyopia
- Interventions
- Phentolamine Opthalmic Solution 0.75%, Placebo, Low dose pilocarpine, Low dose pilocarpine vehicle
- Drug · Other
- Lead sponsor
- Ocuphire Pharma, Inc.
- Industry
- Eligibility
- 40 Years to 64 Years
- Enrollment
- 333 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 26
- States / cities
- Phoenix, Arizona • Azusa, California • Newport Beach, California + 23 more