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ClinicalTrials.gov public records Last synced Oct 30, 2026, 1:12 PM EDT

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Showing 601–624 of 1,661 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Sham (Control) Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Echinacea Purpurea and Osteopathy in Children With Recurrent Otitis Media

NCT00689468
View directory record Official record
Conditions
Otitis Media
Interventions
Cranial osteopathic manipulative treatment., Echinacea purpurea, Sham osteopathic manipulative treatment, "Echinacea purpurea" placebo
Procedure · Dietary Supplement
Lead sponsor
University of Arizona
Other
Eligibility
12 Months to 60 Months
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2002
U.S. locations
3
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 3, 2008 · Synced Oct 30, 2026, 1:12 PM EDT
Terminated Phase 1 Interventional

Quadratus Lumborum Nerve Blocks for Myomectomies

NCT03935815
View directory record Official record
Conditions
Laparoscopic Myomectomy, Quadratus Lumborum Nerve Block
Interventions
Ropivacaine injection, Sham treatment
Drug · Procedure
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older · Female only
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 28, 2021 · Synced Oct 30, 2026, 1:12 PM EDT
Completed Not applicable Interventional

Humanity Neurotech Device Clinical Trial in Adults With Long COVID Cognitive Dysfunction

NCT06739668
View directory record Official record
Conditions
Post-Acute COVID-19 Syndrome, Cognitive Dysfunction
Interventions
Pascal device, Sham Device
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced Oct 30, 2026, 1:12 PM EDT
Completed Phase 3 Interventional Results available

A Study to Compare the Efficacy and Safety of Intravitreal APL-2 Therapy With Sham Injections in Patients With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration

NCT03525613
View directory record Official record
Conditions
Geographic Atrophy
Interventions
APL-2, Sham Procedure
Drug · Other
Lead sponsor
Apellis Pharmaceuticals, Inc.
Industry
Eligibility
60 Years and older
Enrollment
637 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
67
States / cities
Phoenix, Arizona • Bakersfield, California • Beverly Hills, California + 56 more
Source: ClinicalTrials.gov public record
Updated Jul 6, 2023 · Synced Oct 30, 2026, 1:12 PM EDT
Completed Not applicable Interventional

Neuromodulation of Central Sensory Integration to Improve Postural Control

NCT06610617
View directory record Official record
Conditions
Survivorship, Quality of Life, Cognitive Deficits, Mild
Interventions
transcranial direct current stimulation (tDCS), Sham tDCS
Device
Lead sponsor
University of Pittsburgh
Other
Eligibility
50 Years to 85 Years · Female only
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Oct 30, 2026, 1:12 PM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers

Intrauterine Device Insertion Pain Management

NCT06951191
View directory record Official record
Conditions
IUD Insertion Pain, IUD Insertion
Interventions
Benzocaine 20%, Lidocaine 2%, Sham injection, Saline 0.9%
Drug · Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older · Female only
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Oct 30, 2026, 1:12 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Brain Stimulation Enhance Post-stroke Walking Survivors and Healthy Adults

NCT06191549
View directory record Official record
Conditions
Cerebral Vascular Accident
Interventions
anodal transcranial direct current stimulation (a-tDCS)
Combination Product
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
21 Years to 90 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 30, 2026, 1:12 PM EDT
Completed Not applicable Interventional Results available

Effects of a Combined Transcranial Magnetic Stimulation (TMS) and Cognitive Training in Alzheimer Patients

NCT01504958
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
Repetitive Transcranial Magnetic Stimulation (rTMS), NICE Cognitive Training
Device · Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
55 Years to 90 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 30, 2026, 1:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study of the Effectiveness of Green Diode Laser Light on Body Shaping

NCT01292538
View directory record Official record
Conditions
Body Contouring
Interventions
Erchonia GLS, Placebo laser
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
18 Years to 65 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
2
States / cities
Marion, Indiana • Bloomfield Hills, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 10, 2020 · Synced Oct 30, 2026, 1:12 PM EDT
Not yet recruiting Phase 4 Interventional

A Randomized, Placebo-controlled Trial of Nitrous Oxide During In-office Bladder Botox Injections

NCT07387315
View directory record Official record
Conditions
Overactive Bladder, Neurogenic Bladder, Urge Incontinence, Pain, Urinary Incontinence, Urinary Bladder, Overactive, Urinary Bladder, Neurogenic, Urinary Bladder Neurogenesis, Urinary Incontinence, Urge, Pelvic Floor Disorders
Interventions
Pro-Nox Nitrous Oxide/Oxygen Delivery System, Standard Care for Bladder Botox Injection, Sham Mask
Drug · Other
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years and older · Female only
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
2
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Oct 30, 2026, 1:12 PM EDT
Recruiting Phase 2 Interventional

Perivenous Dexamethasone Therapy: Examining Reduction of Inflammation After Thrombus Removal to Yield Benefit in Acute Femoropopliteal DVT

NCT04862468
View directory record Official record
Conditions
Thrombosis, Deep Vein, Iliofemoral; Thrombosis
Interventions
Perivascular dexamethasone, Perivascular sham
Combination Product
Lead sponsor
Mercator MedSystems, Inc.
Industry
Eligibility
18 Years to 89 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2029
U.S. locations
20
States / cities
Scottsdale, Arizona • Orange, California • Darien, Connecticut + 16 more
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 30, 2026, 1:12 PM EDT
Recruiting Not applicable Interventional

Neuromodulation to Regulate Inflammation and Autonomic Imbalance in Sepsis

NCT03992378
View directory record Official record
Conditions
Septic Shock
Interventions
Low Level Transcutaneous Vagus Nerve Stimulation
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Oct 30, 2026, 1:12 PM EDT
Recruiting Not applicable Interventional

A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease

NCT07214376
View directory record Official record
Conditions
Pulmonary Hypertension, Heart Failure With Reduced Ejection Fraction, Hypertension, Vascular Diseases, Cardiovascular Diseases, Heart Failure, Heart Failure With Preserved Ejection Fraction, Heart Failure With Mid Range Ejection Fraction
Interventions
Pulmonary Artery Denervation (PADN), Sham procedure control
Device
Lead sponsor
Pulnovo Medical, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
14
States / cities
Tucson, Arizona • New Haven, Connecticut • Weston, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 30, 2026, 1:12 PM EDT
Completed Not applicable Interventional

Posterior Tibial Nerve Stimulation for Children With Pelvic Floor Dyssynergia

NCT06528470
View directory record Official record
Conditions
Constipation, Fecal Incontinence in Children, Pelvic Floor Dyssynergia
Interventions
Posterior Tibial Nerve Stimulation (PTNS), Sham Stimulation
Device
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
8 Years to 18 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 6, 2026 · Synced Oct 30, 2026, 1:12 PM EDT
Completed Not applicable Interventional

Prospective Evaluation of RINCE to Reduce Fibromyalgia Effects - St. Joseph Mercy Oakland

NCT01825954
View directory record Official record
Conditions
Fibromyalgia
Interventions
RINCE
Device
Lead sponsor
Cerephex Corporation
Industry
Eligibility
22 Years to 65 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Pontiac, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 17, 2015 · Synced Oct 30, 2026, 1:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Investigation of the Role of 905-nm Laser Light in the Delay of Muscle Fatigue

NCT03461731
View directory record Official record
Conditions
Muscle Fatigue
Interventions
Control, 800 nm laser, combination laser, 905 nm laser
Device
Lead sponsor
College of Charleston
Other
Eligibility
18 Years to 25 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 12, 2018 · Synced Oct 30, 2026, 1:12 PM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Controlled Exposure of Healthy Nonsmokers to Secondhand and Thirdhand Cigarette Smoke

NCT04013256
View directory record Official record
Conditions
Pollution; Exposure, Smoke Inhalation, Exposure to Pollution
Interventions
Cigarette Smoke, Clean Air and Clean Clothing/Sham exposure
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 50 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 28, 2023 · Synced Oct 30, 2026, 1:12 PM EDT
Enrolling by invitation Not applicable Interventional

Extension to a Pivotal Study of Sensory Stimulation in Alzheimer's Disease (OLE Hope Study, CA-0015)

NCT06245031
View directory record Official record
Conditions
Alzheimer Disease, Cognitive Impairment, Mild Cognitive Impairment, Dementia, Mild, Dementia Moderate, Dementia Alzheimers, Dementia of Alzheimer Type, AD
Interventions
Sensory Stimulation System (GS120) - Active
Device
Lead sponsor
Cognito Therapeutics, Inc.
Industry
Eligibility
50 Years to 92 Years
Enrollment
402 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
53
States / cities
Phoenix, Arizona • Sun City, Arizona • Anaheim, California + 48 more
Source: ClinicalTrials.gov public record
Updated May 7, 2024 · Synced Oct 30, 2026, 1:12 PM EDT
Completed Not applicable Interventional Results available

Transcranial Magnetic Stimulation (TMS) in Obsessive Compulsive Disorder (OCD): Mechanisms and Biomarkers

NCT02355002
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
Transcranial Magnetic Stimulation
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 13, 2026 · Synced Oct 30, 2026, 1:12 PM EDT
Completed Not applicable Interventional Results available

Transcranial Direct Stimulation (tDCS) and Behavioral Intervention in Aphasia

NCT02226796
View directory record Official record
Conditions
Aphasia
Interventions
Transcranial direct current stimulation
Device
Lead sponsor
University of Minnesota
Other
Eligibility
20 Years to 85 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 18, 2022 · Synced Oct 30, 2026, 1:12 PM EDT
Terminated No phase listed Interventional Results available

Vestibular Stimulation to Trigger Adipose Loss Clinical Trial

NCT03138369
View directory record Official record
Conditions
Obesity, Obesity, Abdominal, Metabolic Syndrome, Weight Loss
Interventions
Vestibular nerve stimulator, Sham vestibular stimulation
Device
Lead sponsor
Neurovalens Ltd.
Industry
Eligibility
22 Years to 80 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 27, 2022 · Synced Oct 30, 2026, 1:12 PM EDT
Recruiting Not applicable Interventional

Investigation of PEMF Therapy for Female Patients With IC/BPS

NCT05149573
View directory record Official record
Conditions
Interstitial Cystitis, Chronic Interstitial Cystitis, Bladder Pain Syndrome
Interventions
Pulsed Electromagnetic Field (PEMF) Device, Sham Pulsed Electromagnetic Field (PEMF) Device
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 30, 2026, 1:12 PM EDT
Recruiting Not applicable Interventional

THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension

NCT06559891
View directory record Official record
Conditions
Hypertension
Interventions
TIVUS™ Renal Denervation System, Sham
Device · Other
Lead sponsor
SoniVie Inc.
Industry
Eligibility
22 Years to 75 Years
Enrollment
261 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
34
States / cities
Birmingham, Alabama • Scottsdale, Arizona • Jonesboro, Arkansas + 30 more
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 30, 2026, 1:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Beta Events and Sensory Perception

NCT04062318
View directory record Official record
Conditions
Beta Rhythm, Tactile Perception
Interventions
Online Active SI-Hand TMS, Online Sham SI-Hand TMS, Online Active Control TMS
Device
Lead sponsor
Brown University
Other
Eligibility
18 Years to 65 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Oct 30, 2026, 1:12 PM EDT