- Conditions
- Sleep, Sleep Disturbance, Insufficient Sleep
- Interventions
- SPP, Sleep Psychoeducation
- Behavioral
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 12 Years to 18 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
Condition Directory
Depression clinical trials
Directory of U.S. ClinicalTrials.gov public records for Depression. Browse Depression recruiting trials, filter by phase, sponsor, location, or intervention, and open the official ClinicalTrials.gov study record for each result.
By Clinical Trials Finder Guidance last reviewed June 10, 2026 Data synced October 26, 2026 Report an issue
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official matching trials
5328
Shown on this page
12
Current sort
Recently updated
Condition scope
Depression
Additional filters apply within this condition.
These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.
How Depression studies are organized in the registry
Most records use the formal term “major depressive disorder” or MDD rather than “depression” alone, and “treatment-resistant depression” (TRD) labels a distinct, sizable subset. The portfolio includes many behavioral, digital, and device interventions, so the intervention and study-type filters do real work here.
Terms that often appear in related listings
These describe how studies tend to be titled and grouped on ClinicalTrials.gov — they are search vocabulary, not medical guidance.
Showing 325–336 of 5,328 matching trials for Depression.
Live ClinicalTrials.gov results.
Live official records
Open in full search- Conditions
- Cancer, Depression
- Interventions
- Technology-Enabled Tailored Referral
- Behavioral
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
- Conditions
- Bipolar Disorder Depression
- Interventions
- Lurasidone (Latuda)
- Drug
- Lead sponsor
- Martin Lan
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Post Partum Depression
- Interventions
- Cognitive behavioral therapy (CBT) psychotherapy group/telehealth, Interpersonal therapy (IPT) psychotherapy group/telehealth
- Behavioral
- Lead sponsor
- Hackensack Meridian Health
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 72 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 1
- States / cities
- Hackensack, New Jersey
- Conditions
- Chronic Back Pain, Depression, Aging, Musculoskeletal Pain
- Interventions
- Behavioral Intervention Group (MOTIVATE)
- Behavioral
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 60 Years to 99 Years
- Enrollment
- 214 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 2
- States / cities
- Dallas, Texas • Houston, Texas
- Conditions
- Depression, Postpartum
- Interventions
- Zuranolone
- Drug
- Lead sponsor
- Biogen
- Industry
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 305 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Woonsocket, Rhode Island
- Conditions
- Major Depressive Disorder
- Interventions
- TMS: single session intermittent theta burst stimulation (iTBS) to dorsomedial prefrontal target in individuals with major depressive disorder, via MagVenture MagPro R30 device / Cool-DB80 A/P coil, SHAM (inactive) TMS stimulation
- Device
- Lead sponsor
- San Francisco Veterans Affairs Medical Center
- Federal
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 98 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2025
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Depression, Depressive Disorder, Major Depressive Disorder, Major Depressive Episode, Depressive Symptoms, Anhedonia
- Interventions
- cross-sectional MRI and EEG assessments (NO INTERVENTION)
- Other
- Lead sponsor
- San Francisco Veterans Affairs Medical Center
- Federal
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 158 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2025
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Depression
- Interventions
- Racemic ketamine, Spravato (Esketamine)
- Drug
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 400 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2030
- U.S. locations
- 8
- States / cities
- Milford, Connecticut • New Haven, Connecticut • Atlanta, Georgia + 5 more
- Conditions
- Major Depression
- Interventions
- Virtual reality
- Behavioral
- Lead sponsor
- Edward Via Virginia College of Osteopathic Medicine
- Other
- Eligibility
- 13 Years to 17 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Washington, Iowa
- Conditions
- Major Depressive Episode, Depression - Major Depressive Disorder, Treatment-Resistant Major Depressive Disorder
- Interventions
- LTFUS to SCC, LTFUS to ALIC
- Device
- Lead sponsor
- Brian Mickey
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Salt Lake City, Utah
- Conditions
- Postpartum Depression
- Interventions
- Zuranolone
- Drug
- Lead sponsor
- Biogen
- Industry
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Cambridge, Massachusetts
About this Depression clinical trials directory page
- What this page lists
- U.S. ClinicalTrials.gov public records that list Depression as a study condition, including recruiting, not yet recruiting, and active not recruiting trials across phase 1, phase 2, and phase 3.
- How to narrow results
- Use the filters above to scope by intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, age, or NCT ID within Depression.
- Where the data comes from
- Records are sourced from the official ClinicalTrials.gov public API. Each result links back to the official study page, which is the source of truth for eligibility, enrollment, and contact information.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, ranking of trials by quality, or AI-generated medical summaries.
Related: all condition pages, browse by drug or therapy, browse by U.S. city, browse by sponsor, or open the full search for Depression.