Home Institutions Duke University Medical Center clinical trials Institution Directory
Clinical trials at Duke University Medical Center Sites in Durham, NC
Institution pages show live ClinicalTrials.gov records that list this campus as a study site, whoever sponsors them. They do not rate, rank, or describe the institution.
ClinicalTrials.gov public records Last synced Oct 24, 2026, 6:36 PM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
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Duke University Medical Center, Durham, NC
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Showing 409–420 of 1,497 matching trials with a site at Duke University Medical Center, Durham, NC.
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Live official records
Conditions Multiple Myeloma
Interventions Talquetamab, Pomalidomide, Teclistamab, Elotuzumab, Dexamethasone, Bortezomib Drug
Lead sponsor Janssen Research & Development, LLC Industry
Eligibility 18 Years and older
Enrollment 838 participants
Healthy volunteers Healthy volunteers not accepted
Timeline 2024 – 2028
U.S. locations 49
States / cities Clovis, California • Santa Monica, California • New Haven, Connecticut + 41 more
Conditions X-Linked Retinitis Pigmentosa
Interventions Genetic: AAV5-hRKp.RPGR Intermediate Dose, Genetic: AAV5-hRKp.RPGR Low Dose Biological
Lead sponsor MeiraGTx Ocular UK Ltd Industry
Eligibility 3 Years and older
Enrollment 97 participants
Healthy volunteers Healthy volunteers not accepted
Timeline 2020 – 2029
U.S. locations 10
States / cities La Jolla, California • Los Angeles, California • Palo Alto, California + 7 more
Conditions Wilson Disease
Interventions UX701, Standard of Care (SOC) Genetic · Drug
Lead sponsor Ultragenyx Pharmaceutical Inc Industry
Eligibility 18 Years and older
Enrollment 82 participants
Healthy volunteers Healthy volunteers not accepted
Timeline 2021 – 2034
U.S. locations 12
States / cities Los Angeles, California • Redwood City, California • Sacramento, California + 9 more
Conditions Healthy
Interventions Multivalent Group B streptococcus vaccine, Placebo, Infanrix hexa, Prevenar 20, Pediarix, Prevnar 20, Infanrix Biological
Lead sponsor Pfizer Industry
Eligibility 1 Day to 49 Years
Enrollment 6,000 participants
Healthy volunteers Accepts healthy volunteers
Timeline 2025 – 2029
U.S. locations 120
States / cities Birmingham, Alabama • Dothan, Alabama • Mobile, Alabama + 56 more
Conditions Prostatic Neoplasms
Interventions Apalutamide, Androgen Deprivation Therapy (ADT), Placebo Drug
Lead sponsor Janssen Research & Development, LLC Industry
Eligibility 18 Years and older · Male only
Enrollment 2,517 participants
Healthy volunteers Healthy volunteers not accepted
Timeline 2019 – 2028
U.S. locations 44
States / cities La Jolla, California • Los Angeles, California • Orange, California + 36 more
Conditions Prostatic Neoplasms, Castration-Resistant
Interventions Pasritamig, Docetaxel, Prednisone/Prednisolone Drug
Lead sponsor Janssen Research & Development, LLC Industry
Eligibility 18 Years and older
Enrollment 800 participants
Healthy volunteers Healthy volunteers not accepted
Timeline 2025 – 2030
U.S. locations 59
States / cities Chandler, Arizona • Little Rock, Arkansas • Fountain Valley, California + 51 more
Conditions Metastatic Prostate Cancer
Interventions JNJ-101556143 Formulation 1, JNJ-101556143 Formulation 2, JNJ-101556143 Formulation 3 Drug
Lead sponsor Janssen Research & Development, LLC Industry
Eligibility 18 Years and older · Male only
Enrollment 190 participants
Healthy volunteers Healthy volunteers not accepted
Timeline 2025 – 2028
U.S. locations 17
States / cities Colorado Springs, Colorado • Denver, Colorado • New Haven, Connecticut + 13 more
Conditions Valve Disease, Heart
Interventions Surgical Heart Valve Repair Products, Surgical Heart Valve Replacement Products Device
Lead sponsor Medtronic Cardiac Surgery Industry
Eligibility Not listed
Enrollment 2,700 participants
Healthy volunteers Healthy volunteers not accepted
Timeline 2019 – 2039
U.S. locations 11
States / cities Marietta, Georgia • Ann Arbor, Michigan • New York, New York + 8 more
Conditions Ischemic Stroke; Ischemic Attack, Transient
Interventions Milvexian, Placebo Drug
Lead sponsor Janssen Research & Development, LLC Industry
Eligibility 40 Years and older
Enrollment 12,523 participants
Healthy volunteers Healthy volunteers not accepted
Timeline 2023 – 2026
U.S. locations 127
States / cities Mesa, Arizona • Tucson, Arizona • Fayetteville, Arkansas + 102 more
Conditions Alzheimer Disease, Dementia, Mild Cognitive Impairment
Interventions Jigsawdio Multisensory Puzzle Platform, Standard Jigsaw Puzzle Activity Behavioral
Lead sponsor Callahan-Young LLC DBA Jigsawdio Industry
Eligibility 60 Years and older
Enrollment 80 participants
Healthy volunteers Healthy volunteers not accepted
Timeline 2026 – 2027
U.S. locations 2
States / cities Durham, North Carolina • College Station, Texas
Conditions Stage II Rectal Cancer AJCC v8, Stage III Rectal Cancer AJCC v8, Locally Advanced Rectal Adenocarcinoma
Interventions Capecitabine, 5-fluorouracil, Leucovorin calcium, Irinotecan, Oxaliplatin, Long Course Chemoradiotherapy, Computed Tomography, Magnetic Resonance Imaging, Sigmoidoscopy, biopsy Drug · Radiation · Procedure
Lead sponsor Alliance for Clinical Trials in Oncology Other
Eligibility 18 Years and older
Enrollment 760 participants
Healthy volunteers Healthy volunteers not accepted
Timeline 2022 – 2037
U.S. locations 679
States / cities Birmingham, Alabama • Mobile, Alabama • Anchorage, Alaska + 483 more
Conditions Metastatic Ewing Sarcoma
Interventions Vincristine, Doxorubicin, Cyclophosphamide, Ifosfamide, Actinomycin, Irinotecan, Cabozantinib, Topotecan, Temozolomide, Etoposide, Liposomal doxorubicin Drug
Lead sponsor H. Lee Moffitt Cancer Center and Research Institute Other
Eligibility 1 Year and older
Enrollment 15 participants
Healthy volunteers Healthy volunteers not accepted
Timeline 2026 – 2030
U.S. locations 21
States / cities Birmingham, Alabama • Phoenix, Arizona • Hartford, Connecticut + 17 more About this Duke University Medical Center institution page
What this page lists ClinicalTrials.gov records that list Duke University Medical Center in Durham, NC as a study site, whoever sponsors them, among recruiting, not yet recruiting, and active not recruiting trials.
Site status A study's overall status can differ from this site's status. Sites marked withdrawn, terminated, or completed are not counted here. Each record shows the status listed for this site when the official record provides one.
Where the data comes from Records are sourced from the official ClinicalTrials.gov public API. Each result links back to the official study page, which is the source of truth for eligibility, enrollment, and contact information.
What this page does not do No medical advice, eligibility judgments, ranking of trials, or AI-generated medical summaries. This page does not rank or rate institutions.
Related: all institution pages , trials led by Duke University at any site , browse by condition , or browse by U.S. city .