- Conditions
- Major Depressive Disorder
- Interventions
- Antidepressant + Placebo, Antidepressant + Aripiprazole
- Drug
- Lead sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 1,200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2006
- U.S. locations
- 20
- States / cities
- Garden Grove, California • Northridge, California • Washington D.C., District of Columbia + 17 more
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.
These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Showing 73–96
of 109
matching trials from the live ClinicalTrials.gov search.
- Conditions
- Major Depressive Disorder
- Interventions
- ALKS 5461, Placebo
- Drug
- Lead sponsor
- Alkermes, Inc.
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 447 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 50
- States / cities
- Little Rock, Arkansas • Bellflower, California • Beverly Hills, California + 45 more
- Conditions
- Major Depressive Disorder
- Interventions
- NBI-1065845, Placebo
- Drug
- Lead sponsor
- Neurocrine Biosciences
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 18
- States / cities
- Little Rock, Arkansas • Garden Grove, California • Orange, California + 15 more
- Conditions
- Major Depressive Disorder
- Interventions
- Lumateperone
- Drug
- Lead sponsor
- Intra-Cellular Therapies, Inc.
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 812 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 40
- States / cities
- Phoenix, Arizona • Bentonville, Arkansas • Little Rock, Arkansas + 35 more
- Conditions
- Major Depressive Disorder
- Interventions
- NBI-1065845, Placebo
- Drug
- Lead sponsor
- Neurocrine Biosciences
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 550 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 24
- States / cities
- Oceanside, California • Orange, California • San Jose, California + 21 more
- Conditions
- Depressive Disorder, Major
- Interventions
- Rapastinel
- Drug
- Lead sponsor
- Naurex, Inc, an affiliate of Allergan plc
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 617 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 128
- States / cities
- Birmingham, Alabama • Dothan, Alabama • Phoenix, Arizona + 104 more
- Conditions
- Major Depression Disorder
- Interventions
- Adjunct brexpiprazole, ADT
- Drug
- Lead sponsor
- H. Lundbeck A/S
- Industry
- Eligibility
- 65 Years and older
- Enrollment
- 132 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 13
- States / cities
- Arcadia, California • Miami, Florida • Orlando, Florida + 9 more
- Conditions
- Major Depressive Disorder
- Interventions
- Cariprazine, Placebo, Antidepressant Therapy (ADT)
- Drug
- Lead sponsor
- Forest Laboratories
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 1,022 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2016
- U.S. locations
- 83
- States / cities
- Tucson, Arizona • Little Rock, Arkansas • Cerritos, California + 68 more
- Conditions
- Major Depressive Disorder
- Interventions
- NBI-1065845, Placebo
- Drug
- Lead sponsor
- Neurocrine Biosciences
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 17
- States / cities
- Huntsville, Alabama • Bryant, Arkansas • Glendale, California + 14 more
- Conditions
- Major Depressive Disorder, Depression
- Interventions
- REL-1017, Placebo
- Drug
- Lead sponsor
- Levomecor Inc.
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 27 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 36
- States / cities
- Dothan, Alabama • Homewood, Alabama • Anaheim, California + 32 more
- Conditions
- Major Depressive Disorder
- Interventions
- Antidepressant + placebo, Antidepressant + cariprazine (0.1-0.3 mg/day), Antidepressant + cariprazine (1-2 mg/d)
- Drug
- Lead sponsor
- Forest Laboratories
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 231 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2010
- U.S. locations
- 41
- States / cities
- Phoenix, Arizona • Scottsdale, Arizona • Arcadia, California + 35 more
- Conditions
- Major Depressive Disorder (MDD)
- Interventions
- LY2216684, Placebo, SSRI
- Drug
- Lead sponsor
- Eli Lilly and Company
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 1,480 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2013
- U.S. locations
- 28
- States / cities
- Birmingham, Alabama • Phoenix, Arizona • Chino, California + 25 more
- Conditions
- Major Depressive Disorder (MDD)
- Interventions
- DT-101, Placebo
- Drug
- Lead sponsor
- Draig Therapeutics Ltd
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 118 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 23
- States / cities
- Phoenix, Arizona • Little Rock, Arkansas • Bellflower, California + 17 more
- Conditions
- Depressive Disorder, Major
- Interventions
- Rapastinel, Placebo
- Drug
- Lead sponsor
- Naurex, Inc, an affiliate of Allergan plc
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 658 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 66
- States / cities
- Birmingham, Alabama • Tucson, Arizona • Little Rock, Arkansas + 56 more
- Conditions
- Major Depressive Disorder
- Interventions
- NBI-1065845
- Drug
- Lead sponsor
- Neurocrine Biosciences
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 850 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2030
- U.S. locations
- 46
- States / cities
- Huntsville, Alabama • Bryant, Arkansas • Little Rock, Arkansas + 40 more
- Conditions
- Depressive Disorder, Major
- Interventions
- Rapastinel, Placebo-matching Rapastinel
- Drug
- Lead sponsor
- Naurex, Inc, an affiliate of Allergan plc
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 1,304 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2019
- U.S. locations
- 137
- States / cities
- Birmingham, Alabama • Dothan, Alabama • Phoenix, Arizona + 112 more
- Conditions
- Major Depressive Disorder
- Interventions
- ALKS 5461, ALKS 5461 Placebo
- Drug
- Lead sponsor
- Alkermes, Inc.
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 278 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2020
- U.S. locations
- 30
- States / cities
- Tucson, Arizona • Little Rock, Arkansas • Los Alamitos, California + 27 more
- Conditions
- Major Depressive Disorder
- Interventions
- 10 mg PRAX-114, 20 mg PRAX-114, 40 mg PRAX-114, 60 mg PRAX-114, Placebo
- Drug
- Lead sponsor
- Praxis Precision Medicines
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 110 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 23
- States / cities
- Lafayette, California • Lemon Grove, California • Oceanside, California + 20 more
- Conditions
- Major Depressive Disorder and Irritability
- Interventions
- Brexpiprazole
- Drug
- Lead sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
- Industry
- Eligibility
- 18 Years to 55 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Atlanta, Georgia
- Conditions
- Adjunctive Treatment of Major Depressive Disorder
- Interventions
- Pimavanserin, Placebo
- Drug
- Lead sponsor
- ACADIA Pharmaceuticals Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 298 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2020
- U.S. locations
- 41
- States / cities
- Birmingham, Alabama • Garden Grove, California • Glendale, California + 34 more
- Conditions
- Depressive Disorder, Major
- Interventions
- Placebo, JNJ-42847922
- Drug
- Lead sponsor
- Janssen Research & Development, LLC
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 287 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2019
- U.S. locations
- 33
- States / cities
- Anaheim, California • Chino, California • Lemon Grove, California + 24 more
- Conditions
- Major Depressive Disorder
- Interventions
- SEP-363856, Placebo
- Drug · Other
- Lead sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 929 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2025
- U.S. locations
- 53
- States / cities
- Birmingham, Alabama • Scottsdale, Arizona • Tucson, Arizona + 45 more
- Conditions
- Depressive Disorder, Depression, Depressive Disorder, Major, Mood Disorders, Mental Disorders
- Interventions
- OPC-34712 + ADT, Placebo + ADT
- Drug
- Lead sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 1,539 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2013
- U.S. locations
- 52
- States / cities
- Birmingham, Alabama • Costa Mesa, California • Glendale, California + 49 more
- Conditions
- Major Depressive Disorder (MDD)
- Interventions
- ADT, Brexpiprazole
- Drug
- Lead sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 61 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 24
- States / cities
- Garden Grove, California • Temecula, California • Orlando, Florida + 21 more