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ClinicalTrials.gov public records Last synced Oct 19, 2026, 2:25 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 442 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Control Rationale Clear all
Recruiting Not applicable Interventional

Engage Coaching (R33 Phase)

NCT07488559
View directory record Official record
Conditions
Social Connection, Loneliness, Suicide Ideation, Social-emotional Quality of Life
Interventions
Social Engage Coaching (S-ENG)
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
60 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 19, 2026, 2:25 AM EDT
Completed Not applicable Interventional Results available

Brain Biomarkers of Response to Treatment for Apraxia of Speech

NCT02046941
View directory record Official record
Conditions
Aphasia, Stroke
Interventions
Speech Production Treatment
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years to 90 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Oct 19, 2026, 2:25 AM EDT
Enrolling by invitation Not applicable Interventional

Comparing Optimized Models of Primary And Specialist Services for Palliative Care

NCT07224594
View directory record Official record
Conditions
Seriously Ill Hospitalized Patients
Interventions
Default Order, Accountable Justification, Standardized Usual Care
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
78,302 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
2
States / cities
Pasadena, California • Livonia, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Oct 19, 2026, 2:25 AM EDT
Terminated Phase 4 Interventional Results available

Safety and Efficacy Study to Compare Smoflipid and Intralipid 20% in Pediatric Patients of 3 Months to 16 Years of Age

NCT03563222
View directory record Official record
Conditions
Malnutrition, Child
Interventions
Smoflipid, Intralipid, 20%
Drug
Lead sponsor
Fresenius Kabi
Industry
Eligibility
3 Months to 16 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 12, 2022 · Synced Oct 19, 2026, 2:25 AM EDT
Completed Phase 4 Interventional

Examining the Effect of Ondansetron on Bowel Prep Success

NCT05439772
View directory record Official record
Conditions
Abdominal Pain, Inflammatory Bowel Diseases, Eosinophilic Gastroenteritis, Diarrhea, Hematochezia, Weight Loss
Interventions
Ondansetron
Drug
Lead sponsor
State University of New York - Downstate Medical Center
Other
Eligibility
2 Years to 20 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Oct 15, 2025 · Synced Oct 19, 2026, 2:25 AM EDT
Completed Not applicable Interventional

Mobile App-based Approach for Reducing Pain and Hazardous Drinking: a Pilot Study

NCT06281821
View directory record Official record
Conditions
Alcohol Drinking, Chronic Pain
Interventions
mhealth-pc
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 26, 2025 · Synced Oct 19, 2026, 2:25 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Artificial Urinary Sphincter Clinical Outcomes

NCT04088331
View directory record Official record
Conditions
Stress Urinary Incontinence
Interventions
AMS 800 Artificial Urinary Sphincter
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older · Male only
Enrollment
145 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
16
States / cities
San Francisco, California • Aurora, Colorado • Iowa City, Iowa + 12 more
Source: ClinicalTrials.gov public record
Updated Jan 14, 2026 · Synced Oct 19, 2026, 2:25 AM EDT
Completed Not applicable Interventional

Comparing Optimized Models of Primary And Specialist Services for Palliative Care: Pilot Feasibility Trial

NCT06629142
View directory record Official record
Conditions
Seriously Ill Hospitalized Patients
Interventions
Default Order, Accountable Justification, Standardized Usual Care
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
1,208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Pasadena, California • Livonia, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 24, 2025 · Synced Oct 19, 2026, 2:25 AM EDT
Recruiting Phase 2 Interventional

Bumetanide in Patients With Alzheimer's Disease

NCT06052163
View directory record Official record
Conditions
Alzheimer Disease
Interventions
Bumetanide, Placebo
Drug
Lead sponsor
Stanford University
Other
Eligibility
50 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jan 14, 2026 · Synced Oct 19, 2026, 2:25 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Smartphone Intervention for Relational and Mental Well Being

NCT04629755
View directory record Official record
Conditions
Depression, Loneliness, Relation, Interpersonal, Covid19
Interventions
Intervention
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
1,765 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 19, 2020 · Synced Oct 19, 2026, 2:25 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Patient Education and Use of Post Operative Pain Medication in Ambulatory Hand Surgery: a Randomized Controlled Trial

NCT03219177
View directory record Official record
Conditions
Ambulatory Hand Surgery
Interventions
Patient education regarding indications for opioid use and side effects of opioid use after hand surgery, Standard of care post-operative counseling
Behavioral · Other
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 16, 2022 · Synced Oct 19, 2026, 2:25 AM EDT
Recruiting Phase 2 Interventional

Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies

NCT04114136
View directory record Official record
Conditions
Melanoma, NSCLC, Hepatocellular Carcinoma, Urothelial Cancer, Gastric Adenocarcinoma, HNSCC, Esophageal Adenocarcinoma, Microsatellite Instability-High Solid Malignant Tumor
Interventions
Nivolumab or Pembrolizumab (dependent upon approved indication), Metformin, Rosiglitazone
Drug
Lead sponsor
Dan Zandberg
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2032
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Oct 19, 2026, 2:25 AM EDT
Terminated Not applicable Interventional

Brief Interventions on Social Media to Reduce Suicide Risk (Intervention 3)

NCT06114849
View directory record Official record
Conditions
Suicide, Distress, Emotional
Interventions
Treatment as usual, Barrier Reduction Intervention
Behavioral
Lead sponsor
Harvard University
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 13, 2025 · Synced Oct 19, 2026, 2:25 AM EDT
Completed Phase 2 Interventional Results available

Belimumab for the Treatment of Diffuse Cutaneous Systemic Sclerosis

NCT01670565
View directory record Official record
Conditions
Systemic Sclerosis
Interventions
Belimumab, Mycophenolate Mofetil, Placebo Infusion
Drug · Other
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 24, 2022 · Synced Oct 19, 2026, 2:25 AM EDT
Recruiting Not applicable Interventional

Factorial Optimization Trial to Test Cognitive Behavioral Therapy Components for Multiple Sclerosis Fatigue

NCT06809192
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
4-session Relaxation Training, 4-session Behavioral Activation, 4-session Cognitive Therapy
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Oct 19, 2026, 2:25 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Neuromodulation of Lidocaine and Capsaicin Cream Effects on Pain Experience

NCT03102710
View directory record Official record
Conditions
Pain
Interventions
transcranial direct current stimulation (tDCS), Lidocaine cream, Capsaicin cream, Control cream
Device · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
21 Years to 50 Years
Enrollment
103 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 7, 2020 · Synced Oct 19, 2026, 2:25 AM EDT
Completed Not applicable Interventional Results available

Mild Cognitive Impairment and Obstructive Sleep Apnea

NCT01482351
View directory record Official record
Conditions
Obstructive Sleep Apnea, Mild Cognitive Impairment
Interventions
CPAP adherence intervention, Attention control intervention
Behavioral
Lead sponsor
George Mason University
Other
Eligibility
55 Years to 89 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
3
States / cities
Abington, Pennsylvania • Philadelphia, Pennsylvania • Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 6, 2019 · Synced Oct 19, 2026, 2:25 AM EDT
Completed Not applicable Interventional

Enhanced Smoking Cessation Intervention for Smokers Exposed to the World Trade Center (WTC) Disaster

NCT02538601
View directory record Official record
Conditions
Cigarette Smoking, Post Traumatic Stress Disorder, Signs and Symptoms, Respiratory
Interventions
CBT-A, CBT-S
Behavioral
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Sep 2, 2015 · Synced Oct 19, 2026, 2:25 AM EDT
Withdrawn Phase 4 Interventional

Study to Assess Safety and Efficacy of Kabiven® in Pediatric Patients 2 to 16 Years of Age

NCT03481894
View directory record Official record
Conditions
Malnutrition
Interventions
Kabiven®, Compounded standard parenteral nutrition
Drug
Lead sponsor
Fresenius Kabi
Industry
Eligibility
2 Years to 16 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
2
States / cities
Chicago, Illinois • Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 4, 2019 · Synced Oct 19, 2026, 2:25 AM EDT
Active, not recruiting Phase 2 Interventional

A Phase II Trial of Limited Surgery and Proton Therapy for Craniopharyngioma or Observation After Radical Resection

NCT01419067
View directory record Official record
Conditions
Craniopharyngioma
Interventions
Radical Surgery or Limited Surgery, Proton Therapy, ^1^8F-fluorodeoxyglucose, ^1^1C-methionine
Procedure · Device · Drug
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
Up to 21 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2031
U.S. locations
2
States / cities
Jacksonville, Florida • Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 19, 2026, 2:25 AM EDT
Terminated Phase 2 Interventional Results available

The Lumen Study: Comparing Devices for Patients With Symptomatic Femoro-popliteal Chronic Total Occlusion (CTO)

NCT02145299
View directory record Official record
Conditions
Symptomatic Femoro-popliteal Chronic Total Occlusion
Interventions
TruePath CTO Device, CROSSER CTO Device
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years to 100 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 4, 2016 · Synced Oct 19, 2026, 2:25 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Microbiome, Bile Acids, and Notch in Barrett's Esophagus (BE)

NCT05524844
View directory record Official record
Conditions
Barrett Esophagus, Esophageal Adenocarcinoma
Interventions
Sample Collection, Endoscopy results, Dietary questionnaire
Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 11, 2025 · Synced Oct 19, 2026, 2:25 AM EDT
Terminated Not applicable Interventional

Randomized Clinical Trial of Early Delivery in Fetal Gastroschisis vs. Routine Care

NCT01884324
View directory record Official record
Conditions
Gastroschisis
Interventions
Early Delivery
Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
16 Years to 50 Years · Female only
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 13, 2017 · Synced Oct 19, 2026, 2:25 AM EDT
Completed Not applicable Interventional Results available

Efficacy of a Smoke-Free Homes Intervention

NCT04547686
View directory record Official record
Conditions
Cessation, Smoking
Interventions
Smoke-Free Homes Intervention, Quitline
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
916 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 19, 2026, 2:25 AM EDT