- Conditions
- Atrial Fibrillation, Stroke
- Interventions
- CLAAS, WATCHMAN left atrial appendage closure device / Amulet left atrial appendage occluder
- Device
- Lead sponsor
- Conformal Medical, Inc
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 1,600 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2031
- U.S. locations
- 78
- States / cities
- Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 66 more
Search Results
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Showing 1–24
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- Conditions
- Atrial Fibrillation
- Interventions
- Not listed
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2008
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Atrial Fibrillation, Ischemic Stroke, Acute
- Interventions
- Left Atrial Appendage Occlusion
- Other
- Lead sponsor
- Kansas City Heart Rhythm Research Foundation
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Overland Park, Kansas
- Conditions
- Atrial Fibrillation, Stroke, Bleeding
- Interventions
- Left Atrial Appendage Occlusion (Amplatzer Amulet LAA Occluder), Non-Vitamin K Oral Antagonists
- Device · Drug
- Lead sponsor
- Abbott Medical Devices
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 2,650 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2031
- U.S. locations
- 79
- States / cities
- Birmingham, Alabama • Huntsville, Alabama • Phoenix, Arizona + 65 more
- Conditions
- Atrial Fibrillation
- Interventions
- Not listed
- Lead sponsor
- CorVita Science Foundation
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2027
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Atrial Fibrillation, Left Atrial Appendage Thrombosis, CVA
- Interventions
- LAmbre PlusTM Left Atrial Appendage Closure System, Market approved oral anticoagulation (OAC), such as warfarin (Coumadin), dabigatran (Pradaxa), rivaroxaban (Xarelto), apixiban (Eliquis), edoxaban (Savaysa), or betrixaban (Bevyxxa)
- Device · Drug
- Lead sponsor
- Brian O'Neill MD
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- Detroit, Michigan
- Conditions
- Atrial Fibrillation, Stroke, Bleeding
- Interventions
- Left atrial appendage occlusion (LAAO)
- Device
- Lead sponsor
- Abbott Medical Devices
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 610 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 16
- States / cities
- Phoenix, Arizona • Little Rock, Arkansas • Jacksonville, Florida + 13 more
- Conditions
- Left Atrial Appendage Occlusion
- Interventions
- Medtronic LAA Occlusion Device
- Device
- Lead sponsor
- Medtronic Cardiovascular
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2010
- U.S. locations
- 5
- States / cities
- Rancho Mirage, California • New Haven, Connecticut • Chicago, Illinois + 2 more
- Conditions
- Atrial Fibrillation
- Interventions
- 4D ICE Adjunct Imaging
- Device
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Atrial Fibrillation, Stroke
- Interventions
- WATCHMAN Left Atrial Appendage Closure Technology, Warfarin
- Device · Drug
- Lead sponsor
- Boston Scientific Corporation
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 800 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2014
- U.S. locations
- 58
- States / cities
- Gilbert, Arizona • Scottsdale, Arizona • La Jolla, California + 46 more
- Conditions
- Device-Related Thrombosis, Atrial Fibrillation, Left Atrial Appendage Occlusion
- Interventions
- ASA plus Clopidogrel, Genetic-Tailored AntiThrombotic Strategy, Half-Dose of novel OAC
- Drug
- Lead sponsor
- Texas Cardiac Arrhythmia Research Foundation
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 360 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2023
- U.S. locations
- 1
- States / cities
- Austin, Texas
- Conditions
- Left Atrial Appendage Incomplete Closure
- Interventions
- Interlock-35 Fibered IDC Occlusion System, Concerto Helix Detachable Coil System, Azur Peripheral Coil System
- Device
- Lead sponsor
- Texas Cardiac Arrhythmia Research Foundation
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Austin, Texas
- Conditions
- Atrial Fibrillation
- Interventions
- LARIAT LAA, WATCHMAN
- Device
- Lead sponsor
- Kansas City Heart Rhythm Institute
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 169 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2018
- U.S. locations
- 1
- States / cities
- Kansas City, Kansas
- Conditions
- Atrial Fibrillation
- Interventions
- LARIAT Suture Delivery Device and Accessories
- Device
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 21 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2014
- U.S. locations
- 10
- States / cities
- Phoenix, Arizona • San Diego, California • San Francisco, California + 6 more
- Conditions
- Persistent Atrial Fibrillation
- Interventions
- cryoballoon ablation
- Device
- Lead sponsor
- Staten Island University Hospital
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 62 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Left Atrial Appendage Closure With WATCHMAN Device Utilizing an Intra-procedural ICE Probe
- Interventions
- WATCHMAN device implant procedure utilizing ICE probe
- Procedure
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 101 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2023
- U.S. locations
- 2
- States / cities
- Santa Monica, California • Rochester, Minnesota
- Conditions
- Stroke
- Interventions
- Coherex WaveCrest® Left Atrial Appendage Occlusion System, Watchman® LAA Closure Device
- Device
- Lead sponsor
- Coherex Medical
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 248 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2023
- U.S. locations
- 23
- States / cities
- Birmingham, Alabama • Chandler, Arizona • Los Angeles, California + 18 more
- Conditions
- Device Related Thrombosis, Peri-device Leak
- Interventions
- Transesophageal echocardiography (TEE), Cardiac CTA
- Procedure
- Lead sponsor
- University Hospitals Cleveland Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 320 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026
- U.S. locations
- 5
- States / cities
- Los Angeles, California • Roslyn, New York • Charlotte, North Carolina + 2 more
- Conditions
- Coronary Artery Disease, Atrial Fibrillation (AF)
- Interventions
- Hybrid procedure, Endocardial ablations, left atrial appendage occlusion
- Procedure
- Lead sponsor
- Cardiovascular Innovation and Research Institute
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1,000 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2030
- U.S. locations
- 1
- States / cities
- Glenwood Springs, Colorado
- Conditions
- Atrial Fibrillation
- Interventions
- VARIPULSE Catheter System, LAAO Device
- Device
- Lead sponsor
- Biosense Webster, Inc.
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 1,070 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2031
- U.S. locations
- 3
- States / cities
- Tucson, Arizona • Jonesboro, Arkansas • The Bronx, New York
- Conditions
- Non-valvular Atrial Fibrillation
- Interventions
- left atrial appendage closure
- Device
- Lead sponsor
- Conformal Medical, Inc
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 64 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2028
- U.S. locations
- 11
- States / cities
- Jonesboro, Arkansas • Santa Monica, California • Manchester, New Hampshire + 7 more
- Conditions
- Atrial Fibrillation, Stroke, Ischemic, Systemic Embolism
- Interventions
- WATCHMAN device
- Device
- Lead sponsor
- Hamilton Health Sciences Corporation
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 4,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2029
- U.S. locations
- 50
- States / cities
- Birmingham, Alabama • Jonesboro, Arkansas • Fountain Valley, California + 45 more
- Conditions
- Heart Diseases
- Interventions
- LAAx, Inc. TigerPaw® System II
- Device
- Lead sponsor
- LAAx, Inc.
- Industry
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015
- U.S. locations
- 4
- States / cities
- Pleasanton, California • Baltimore, Maryland • Danville, Pennsylvania + 1 more
- Conditions
- Atrial Fibrillation, Atrial Arrhythmia
- Interventions
- Data collection
- Other
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 198 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 10
- States / cities
- Chicago, Illinois • Evanston, Illinois • Boston, Massachusetts + 4 more